World · Bio/Biochem + Chem/Phys
Amino acids, enzymes, DNA and the metabolism maps everyone pretends to have memorized.
Unit 1 · 6 skills
Building blocks, peptide bonds and how proteins fold.
Amino acid structure and classification
Amino acid charge and pI
Peptide bonds and hydrolysis
Primary to quaternary structure
Folding, denaturation and stability
Nonenzymatic protein functions
Unit boss
Unit 2 · 4 skills
How enzymes speed things up, and how we slow them down.
Enzyme classes and catalysis
Michaelis-Menten kinetics
Enzyme inhibition
Allosteric and covalent regulation
Unit boss
Unit 3 · 4 skills
Sugars, fats and the molecules built from them.
Monosaccharides and stereochemistry
Disaccharides and polysaccharides
Lipid structure and types
Steroids and lipid signaling
Unit boss
Unit 4 · 4 skills
Nucleotides, the double helix and keeping the genome intact.
Nucleotide structure
The DNA double helix
DNA replication
DNA repair and mutation
Unit boss
Unit 5 · 5 skills
From gene to protein, and how cells decide what to make.
Transcription
RNA processing
Translation
Prokaryotic gene regulation
Eukaryotic gene regulation
Unit boss
Unit 6 · 4 skills
PCR, gels, blots and cloning.
PCR and DNA amplification
Gel electrophoresis
Southern, Northern and Western blots
Cloning and recombinant DNA
Unit boss
Unit 7 · 5 skills
What gets in, what gets out, and what it costs.
The fluid mosaic model
Diffusion and osmosis
Active transport and pumps
Membrane potential
Membrane receptors and signaling
Unit boss
Unit 8 · 4 skills
Turning glucose into ATP, step by step.
Glycolysis
Pyruvate oxidation and the Krebs cycle
The electron transport chain
Oxidative phosphorylation and ATP yield
Unit boss
Unit 9 · 6 skills
Storage, backup fuels and the pathways in between.
Glycogen metabolism
Gluconeogenesis
The pentose phosphate pathway
Fatty acid oxidation
Ketone bodies
Amino acid breakdown
Unit boss
Unit 10 · 4 skills
Hormones, fed and fasting states, and who burns what.
Insulin, glucagon and hormones
Fed and fasting states
Tissue-specific metabolism
Metabolic disorders
Unit boss
Final boss · Timed
Beat every unit boss in this world to unlock a timed mini-section.